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Odds, lines, picks, spreads, bets, NFL predictions, what to bet for Week 18, 2025: Packers and Rams in love with the models

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With a half-dozen games before Sunday in last week’s NFL schedule, that means many teams are resting with either advantages or disadvantages in Week 18 of the NFL schedule. One of the latter is the Raiders, who will face a Chargers team that played Saturday. However, despite having one of the NFL’s worst records since 2022, the Raiders own the league’s best ATS record on less rest than their opponent. Vegas is 10-1 against the spread in these situations since 2022 and the team is a 5.5-point underdog against Los Angeles in Week 18. NFL Odds. This line sits roughly in the middle of the pack compared to the rest of the NFL’s Week 18 spreads.

The final slate of regular season games includes five NFL games with Week 18 NFL betting lines less than a field goal and five games with a line more than a touchdown. Matchups include Bills vs. Patriots (+2.5, 38), 49ers vs. Cardinals (-4.5, 42.5) and Lions vs. Vikings (+3, 57). All updated NFL lines from Week 18 are listed below, and SportsLine’s advanced computer model has all the NFL betting tips and NFL predictions you need to make the best NFL picks for Week 18 now..

The model, which simulates every NFL game 10,000 times, costs well over $7,000 for $100 players among the NFL’s top-rated picks since its inception. The model enters Week 18 of the 2024 NFL season on a 30-14 top-rated hot betting streak. NFL Pick this year, a staggering 68% success rate. Longer term, he’s 210-142 on top-rated NFL picks dating back to the 2017 season and 64-35 on top-rated NFL picks dating back to Week 7 of 2022.

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The model has also ranked in the top 10 on NFLPickWatch four of the last six years on straight NFL picks and has beaten more than 94% of CBS Sports Football Pick’em players four times during that span. Anyone who follows sports betting and betting apps has seen solid returns.

Now he turns his attention to the latest Week 18 NFL Odds and NFL betting lines and locked betting picks for every NFL game. Head here to see each choice.

Best NFL Predictions for Week 18

We can tell you that one of the model’s strongest picks for NFL Week 18 is the Rams (+5.5, 39) covering the spread at home against the Seahawks. Los Angeles clinched the NFC West in Week 17, but still has a seed on the line in Week 18. It could finish as the No. 3 seed with a win, however, a loss could dropping to No. 4 and a potential wild card match. against a 14-win Lions or Vikings team. So, there’s a lot at stake for Los Angeles on Sunday, unlike Seattle which was eliminated from the playoffs.

Sean McVay is 11-5 against Seattle since becoming head coach of the Rams in 2017, and his team has covered in seven of its last eight games against Seattle. The Rams have won their last five games overall, going 4-1 ATS, while Seattle has lost three straight ATS games. The Seahawks are also coming off a terrible performance against Chicago in which they failed to find the end zone, scoring just six points. The model has Los Angeles prevailing over the spread well over 50% of the time. Find out which other teams to choose here.

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Another of his NFL predictions for Week 18: The Packers (-9.5, 40.5) cover at home against the Bears. Green Bay is currently the No. 7 seed, but needs to win and get some help to clinch the No. 6 seed. Winning is all the Packers have done in this game recently as they have beaten the Bears in each of their last 11 meetings. Green Bay is 10-1 ATS in these contests, and Chicago’s struggles aren’t limited to this head-to-head series. The Bears enter this game on a 10-game losing streak, which is the second-longest losing streak in the franchise’s 105-year history.

Caleb Williams has been sacked 67 times, 15 more than any other quarterback this season, and Green Bay has one of the best passing offenses. Only six teams have more sacks than the Packers (44), while Chicago has gaps all over its offense. The Bears rank in the bottom four in the NFL in points scored, yards gained, passing offense and third-down offense. With these factors, the model covers the Packers in nearly 60% of simulations. The model also indicates that the Over hits well over 60% of the time. Find out which other teams to choose here.

How to make Week 18 NFL picks

The model also asked who wins and covers every other game on the NFL’s Week 18 schedule and just revealed four teams that win outright more than 70% of the time, potentially earning you a huge payday. You can only get every pick for every game at SportsLine.

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So which NFL picks can you make with confidence and which four teams should you lock in now? Discover the latest NFL Odds below, then visit SportsLine to see which teams are winning and covering the spread, all from a proven computer model that has returned well over $7,000and find out.

Week 18 Odds, Lines, Live Spreads, NFL Betting Scores

Get NFL Picks for Week 18 at SportsLine

Where to bet on NFL games

Here are some of the sportsbooks to bet on for NFL games this week, as well as the different NFL sports betting promotions they are currently offering.

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