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Week 18, 2025: NFL predictions, odds and game picks: Model shares exact scores from 10,000 simulations

Week 18 2025 NFL predictions odds and game picks Model Week 18 2025 NFL predictions odds and game picks Model
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The NFL regular season ends in Week 18 and several NFL matchups have major playoff implications. The Detroit Lions and Minnesota Vikings will face off in an NFC North battle that will determine the No. 1 seed in the NFC playoff bracket. The Lions posted a 31-29 win over Minnesota on the road in October and are favored by three points in the latest NFL Week 18 odds. Detroit has won four straight against the Vikings, but should you include the Lions in your NFL betting picks for Week 18?

Other notable Week 18 spreads in the NFL include Bengals vs. Steelers (+1.5, 48), Chiefs vs. Broncos (-10.5, 39.5) and Saints vs. Buccaneers (-13 .5, 43.5). Making NFL score predictions for Week 18 can help form not only NFL spread picks, but also NFL over-under picks, NFL parlays, and even a Week 18 survivor strategy of the NFL. Which NFL Week 18 games will be lopsided and which will be played closer to their spreads? Before making any NFL Week 18 picks, be sure to find out what SportsLine’s advanced computer model has to say.

The model, which simulates every NFL game 10,000 times, costs well over $7,000 for $100 players among the NFL’s top-rated picks since its inception. The model enters Week 18 of the 2024 NFL season on an incredible 30-14 top-rated hot betting streak. NFL Pick this year, a staggering 68% success rate. Longer term, he’s 210-142 on top-rated NFL picks dating back to the 2017 season and 64-35 on top-rated NFL picks dating back to Week 7 of 2022.

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The model has also ranked in the top 10 on NFLPickWatch four of the last six years on straight NFL picks and has beaten more than 94% of CBS Sports Football Pick’em players four times during that span. Everyone who follows sports betting and betting apps has seen strong returns on their best sports betting app.

Now the model has simulated every game in Week 18 10,000 times. You can only see the model’s exact score predictions for NFL Week 18 at SportsLine.

Top NFL Picks of Week 18

After diving into every game on the Week 18 NFL schedule, the model backs the Green Bay Packers (-10, 41) to beat the Chicago Bears, 28-17. The Packers have already clinched a playoff spot, but they can improve their position with a win and a Commanders loss.

Green Bay has dominated this rivalry over the years, winning 11 straight games against the Bears. The Packers recorded a 20-19 victory over Chicago on the road in November thanks to a strong performance from quarterback Jordan Love. The Green Bay signal-caller threw for 261 yards and a touchdown, while rushing for 18 yards and another score. Love was effective down the stretch against the Packers, racking up nine passing touchdowns and no interceptions over his last six games.

The Bears, meanwhile, enter Sunday’s game having lost each of their last 10 games. Chicago has lost nine straight on the road and is 1-10 ATS in its last 11 games against Green Bay. The model projects Love to throw for over 250 yards and 1.91 touchdowns, while Green Bay’s defense averages 4.56 sacks. See the model’s other NFL score predictions for Week 18 at SportsLine.

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How to Make NFL Score Predictions for Week 18

Additionally, the model has locked in exact score predictions for this week’s biggest matchups, including Bengals vs. Steelers, Chiefs vs. Broncos, and Vikings vs. Lions. It also takes a surprising underdog to pull off a shocking upset. Getting these results is key to making profitable NFL Week 18 picks. You can only see them on SportsLine.

Who wins every NFL Week 18 game and which underdog pulls off a shocking upset? Visit SportsLine now to get the model’s NFL Week 18 score predictions, all from the model at 210-142 on the NFL’s highest-rated picks.and find out.

Where to bet on NFL games

Here are the best sportsbooks to bet on for NFL games this week, as well as the different NFL sports betting promotions they are currently offering.

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